Novartis’s Heartache over Entresto: An Analysis of the Controller’s Patent Revocation Decision
[The post is co-authored with Vikram Raj Nanda. A big thanks to Swaraj and Praharsh for their inputs.] In a detailed 262-page order (pdf) dated 12th September, 2025, Dr Usha Rao, the Deputy Controller of Patents and Designs, annulled Novartis’ patent over its cardiac drug ‘Vymada’ (marketed internationally as ‘Entresto’). The Controller had cumulatively dealt with several post-grant oppositions that had been filed by the Indian Pharmaceutical Alliance, along with two firms: IPCA (Indian Pharmaceutical Combine Association) Laboratories and MicroLabs. […]










